A retrospective, one-year case-control study was conducted in Pakistan that aimed to compare the odds of positive outcomes in myasthenia gravis (MG) patients with or without thymectomy. It is believed that the thymus gland is responsible for producing the antibodies that affect the neuro-muscular junction on the postsynaptic membrane. Screening patients for thymoma and surgical excision of the thymus gland is an important part of MG treatment. The research findings indicated that none of the analyzed groups had significantly worse outcomes as a result of the current clinical practice of thymectomy patient selection.

Reference: Khawaja I. Effect of Thymectomy on Outcomes of Myasthenia Gravis Patients: A Case-Control Study at a Tertiary Care Hospital. Cureus. 2023 Apr 14;15(4):e37584. doi: 10.7759/cureus.37584. PMID: 37193448; PMCID: PMC10183232.