This guide provides practical insights into diagnosing and managing multiple system atrophy (MSA), focusing on the newly released Movement Disorders Society Consensus Diagnostic Criteria. These criteria aim to streamline diagnosis through categorizing MSA into distinct clinical stages, potentially reducing the time to diagnosis. Key clinical features aiding diagnosis are outlined, along with methods to differentiate MSA from its mimics. Additionally, the guide discusses symptom management strategies to enhance the quality of life for individuals living with MSA.

MSA is a progressive neurological disease marked by parkinsonism, cerebellar dysfunction, and autonomic disturbances. Diagnosing MSA can be challenging, often leading to delayed diagnosis and significant impact on patient well-being. The guide emphasizes early recognition and comprehensive diagnostic evaluation, including clinical history, examination findings, and neuroimaging. Furthermore, it addresses practical strategies for managing MSA symptoms, highlighting the importance of multidisciplinary care and early involvement of allied health professionals.

Reference: Goh YY, Saunders E, Pavey S, et al. Multiple system atrophy. Pract Neurol. 2023 Jun;23(3):208-221. doi: 10.1136/pn-2020-002797. Epub 2023 Mar 16. PMID: 36927875; PMCID: PMC10314081.